How does Microneedling work?
Natural hair growth is dependent on the genetic make-up of an individual to support the development of new hair cells. This cellular regeneration occurs within the hair follicles, which are the tiny openings that cover the scalp. A combination of chemicals is required to trigger the production of these cells, including a very important factor called the human growth factor.
Microneedling therapy is designed to trigger the targeted production of this human growth factor. When the micro needles are pricked into the scalp, it causes superficial and minor wounds to the tissue surface. This prompts the body to set the mechanism in motion for skin regeneration in the area of the wound. Human growth hormone and related growth chemicals are released in this process. Microneedling therapy essentially involves gentle pricking into the layers of the skin of the scalp. This process is designed to open the pores for optimal absorption of topical treatments. Sustained application of microneedling and use of topical treatment combination has revealed outstanding results in the scalp health and hair regrowth that lasts even after eight months.
Recent scientific studies for hair loss have focused on the innovative microneedling therapy for the scalp. Results with this non-invasive therapy to fight back hair loss and hair thinning, and promoting the growth of new hair on the scalp have been very encouraging. Some of the clinical studies have also shown that a combination of micro needling therapy and topical treatments on the scalp may produce highly effective outcomes.
What topical treatments are available in combination with microneedling?
There are a variety of topical treatments available to use in combination with microneedling today, from PRP to Minoxidil. At Anna Burns Permanent Cosmetics, we use growth factors and natural oils in combination with microneedling for hair loss treatment.
What are Growth Factors?
The science of growth factors as an anti-aging skin technology moved forward a great deal through the work of scientists Stanley Cohen and Rita Levi-Montalcini, who were awarded the Nobel Prize in Medicine in 1986 for advancing understanding of the role of Epidermal Growth Factor (EGF) in cell biology. Other researchers continued studying EGF, leading to current clinical applications of EGF for skin conditions and reversing the signs of aging. EGF is known to considerably increase skin cell regeneration, and studies have shown that it significantly aids in the healing of skin wounds.
Since the work of Cohen and Levi-Montalcini, scientific research has built a knowledge base of types and functions of other major GF, including TGF-b (Transforming Growth Factor), PDGF (Platelet Derived Growth Factor), GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor), and IL (Interleukins). Medical research has found that GF can speed and improve healing when applied to areas of the human body damaged in surgery, burns, wounds, or accidents. The mechanism behind the benefits is facilitation of changes at the cellular level to revert damaged cells to a younger state, healing the damaged skin in the process. Some researchers wondered if the same GF-technology that was bringing such remarkable healing results to skin injuries could bring about cosmetic benefits as well. Scientists found that GF-technology had the potential to reverse the cell aging process, fade scars, improve healing, and renew the hair follicles on the scalp to help people with thinning hair. GF-technology is now being shown to improve the appearance of aging and sun-damaged skin and to help restore normal hair growth. Cosmetic patents of early GF-technology were first issued in 1994.
In 2001, two independent double-blind studies testing topical creams containing either natural or bio-engineered GF were presented to the Society of Investigative Dermatology. The results were surprising—when applied to skin twice a day for four–six weeks, both types of creams produced better results than Botox! Each study showed significant increases in production of collagen, hyaluronic acid, elastin, fibroblasts, and epidermal thickness.
Growth factors (GF) are found in many different cell types in the human body. They are a group of specialized proteins with many functions, the most important being the activation of cellular proliferation and differentiation. Growth factors turn essential cellular activities “on” and “off,” and they play a role in increasing cell production, cell division, blood vessel production, and collagen and elastin production.
The skin and scalp contain multiple growth factors that regulate natural cellular renewal and damage repair processes to keep skin healthy and to maintain a normal hair growth cycle. These growth factors are responsible for helping to reverse the visible effects of chronological aging and premature aging due to environmental factors. The consequences of environmental exposure and the normal processes of aging lead to excessive free radical damage of skin and scalp cellular components, resulting in the breakdown of collagen and elastin networks in the dermis and producing the effect of visible facial aging. This same type of damage eventually impairs growth factor function, so they are less able to repair oxidative damage, and the damage becomes permanent.
Advances in GF-technology are providing help for reversing the signs of aging. Growth factors can now be produced in a laboratory for topical use. In multiple clinical studies, topically applied GF have been shown to reduce the signs of skin aging, including statistically significant reductions in fine lines and wrinkles and increases in dermal collagen synthesis. GF-technology is also being used successfully for encouraging healthy hair growth, reducing the appearance of scars, supporting the skin during post-procedure healing, and shortening the healing time of burn wounds.